At the start, the gradient of the curve is the steepest. This shows that speed of reaction is the highest at the start. The concentration of the reacting particles is the highest at the start, resulting in highest speed of reaction.
As the reaction progresses, the gradient of the curve decreases. This shows that speed of reaction is slowing down. As the reactants are used up in the reaction, the concentration of reacting particles decreases, resulting in a decrease in speed of reaction.
When the gradient of the curve becomes horizontal, it shows that the reaction has stopped. Either one or all of the reactants have been completely used up, so reaction stopped.